Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome

N-acetyl-l-leucyl-l-leucyl-l-norleucinal (LLnL), which reversibly inhibits the proteasome in addition to other proteases, and a more specific irreversible inhibitor of the proteasome, lactacystin, were found to cause the accumulation of major histocompatibility complex (MHC) class I heavy chains in...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hughes, Eric A., Hammond, Craig, Cresswell, Peter
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9050876/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.5.1896
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