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Enhancing Th2 immune responses against amyloid protein by a DNA prime-adenovirus boost regimen for Alzheimer’s disease

Accumulation of aggregated amyloid β-protein (Aβ) in the brain is thought to be the initiating event leading to neurodegenetation and dementia in Alzheimer’s disease (AD). Therefore, therapeutic strategies that clear accumulated Aβ and/or prevent Aβ production and its aggregation are predicted to be...

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Detalhes bibliográficos
Main Authors: Kim, Hong-Duck, Jin, Jing-Ji, Maxwell, J. Adam, Fukuchi, Ken-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001313/
https://ncbi.nlm.nih.gov/pubmed/17686533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2007.06.006
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