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Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
BACKGROUND: Aβ deposits in the brains of patients with Alzheimer's disease (AD) are closely associated with innate immune responses such as activated microglia and increased cytokines. Accumulating evidence supports the hypothesis that innate immune/inflammatory responses play a pivotal role in...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430555/ https://ncbi.nlm.nih.gov/pubmed/18510752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-23 |
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