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The molecular basis for recognition of different substrates by phosphodiesterase families 4 and 10
Phosphodiesterases (PDEs) are key enzymes that control the cellular concentrations of the second messengers cAMP and cGMP. The mechanism for selective recognition of substrates cAMP and cGMP by individual PDE families remains a puzzle. To understand the mechanism for substrate recognition by PDE enz...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2001251/ https://ncbi.nlm.nih.gov/pubmed/17582435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.05.060 |
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