Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration

Dopaminergic cells in the substantia nigra are highly vulnerable to the neurodegenerative process of Parkinson’s disease. Therefore, mechanisms that enhance their susceptibility to injury bear important implications for disease pathogenesis. Repeated injections with the herbicide paraquat cause oxid...

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Bibliografiske detaljer
Main Authors: Purisai, Maya G., McCormack, Alison L., Cumine, Suzanne, Li, Jie, Isla, Martha Z., Di Monte, Donato A.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001246/
https://ncbi.nlm.nih.gov/pubmed/17166727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2006.10.008
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