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Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration

Dopaminergic cells in the substantia nigra are highly vulnerable to the neurodegenerative process of Parkinson’s disease. Therefore, mechanisms that enhance their susceptibility to injury bear important implications for disease pathogenesis. Repeated injections with the herbicide paraquat cause oxid...

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Hlavní autoři: Purisai, Maya G., McCormack, Alison L., Cumine, Suzanne, Li, Jie, Isla, Martha Z., Di Monte, Donato A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001246/
https://ncbi.nlm.nih.gov/pubmed/17166727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2006.10.008
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