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Pharmacokinetics, safety and tolerance of single- and multiple-dose adefovir dipivoxil in healthy Chinese subjects

AIMS: To assess the pharmacokinetics, safety and tolerance of single- and multiple-dose adefovir dipivoxil (ADV) in healthy Chinese subjects. METHODS: Forty-two healthy subjects were randomized into 5, 10, 20, 40 and 60-mg dose groups for safety assessment. Nine and 10 healthy males were enrolled fo...

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Bibliografiske detaljer
Main Authors: Sun, De-qing, Wang, Hai-sheng, Ni, Mei-yuan, Wang, Ben-jie, Guo, Rui-chen
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000720/
https://ncbi.nlm.nih.gov/pubmed/16869815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02728.x
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