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Single-dose FTY720 pharmacokinetics, food effect, and pharmacological responses in healthy subjects

AIMS: FTY720 is a sphingosine-1-phosphate receptor agonist that redirects lymphocytes from the circulation to lymph nodes without impairing lymphocyte function. It is being developed as an immunomodulator for the prevention of acute rejection after organ transplantation. This study was performed to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kovarik, John M, Schmouder, Robert, Barilla, Denise, Wang, Yibin, Kraus, Gerolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884502/
https://ncbi.nlm.nih.gov/pubmed/15089811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2003.02065.x
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