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Single-dose FTY720 pharmacokinetics, food effect, and pharmacological responses in healthy subjects

AIMS: FTY720 is a sphingosine-1-phosphate receptor agonist that redirects lymphocytes from the circulation to lymph nodes without impairing lymphocyte function. It is being developed as an immunomodulator for the prevention of acute rejection after organ transplantation. This study was performed to...

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Detalhes bibliográficos
Main Authors: Kovarik, John M, Schmouder, Robert, Barilla, Denise, Wang, Yibin, Kraus, Gerolf
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884502/
https://ncbi.nlm.nih.gov/pubmed/15089811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2003.02065.x
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