Impact of atorvastatin treatment on platelet-activating factor acetylhydrolase and 15-F(2trans)-isoprostane in hypercholesterolaemic patients

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Isoprostanes are the product of free radical oxidation of arachidonic acid bound to phospholipids. Their hydrolysis from phospholipids is presumably catalysed by phospholipases A(2). Atorvastatin reduces protein concentrations of secretory PLA(2)s and concen...

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Detalles Bibliográficos
Main Authors: Kom, Ghainsom D, Schwedhelm, Edzard, Maas, Renke, Schneider, Lydia, Benndorf, Ralf, Böger, Rainer H
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2007
Assuntos:
Pharmacodynamics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000588/
https://ncbi.nlm.nih.gov/pubmed/17214829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02832.x
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