Impact of atorvastatin treatment on platelet-activating factor acetylhydrolase and 15-F(2trans)-isoprostane in hypercholesterolaemic patients

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Isoprostanes are the product of free radical oxidation of arachidonic acid bound to phospholipids. Their hydrolysis from phospholipids is presumably catalysed by phospholipases A(2). Atorvastatin reduces protein concentrations of secretory PLA(2)s and concen...

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Bibliografske podrobnosti
Main Authors: Kom, Ghainsom D, Schwedhelm, Edzard, Maas, Renke, Schneider, Lydia, Benndorf, Ralf, Böger, Rainer H
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2007
Teme:
Pharmacodynamics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000588/
https://ncbi.nlm.nih.gov/pubmed/17214829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02832.x
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