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P2Y(12) polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease

AIMS: Recently, two genetic polymorphisms of the platelet ADP receptor P2Y(12) (haplotypes H2 and 34T) have been implicated in increased platelet aggregation and atherothrombotic risk. It was suggested that these polymorphisms contribute to a diminished response to antiplatelet drugs. Therefore, we...

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Hlavní autoři: Bierend, Anneke, Rau, Thomas, Maas, Renke, Schwedhelm, Edzard, Böger, Rainer H
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291388/
https://ncbi.nlm.nih.gov/pubmed/17995973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03044.x
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