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Structural determination of wild-type lactose permease

Here we describe an x-ray structure of wild-type lactose permease (LacY) from Escherichia coli determined by manipulating phospholipid content during crystallization. The structure exhibits the same global fold as the previous x-ray structures of a mutant that binds sugar but cannot catalyze translo...

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Bibliographic Details
Main Authors: Guan, Lan, Mirza, Osman, Verner, Gillian, Iwata, So, Kaback, H. Ronald
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000551/
https://ncbi.nlm.nih.gov/pubmed/17881559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707688104
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