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Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo

Gab1 is a multiadaptor protein that has been shown to be required for multiple processes in embryonic development and oncogenic transformation. Gab1 functions by amplifying signal transduction downstream of various receptor tyrosine kinases through recruitment of multiple signaling effectors, includ...

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Библиографические подробности
Главные авторы: Schaeper, Ute, Vogel, Regina, Chmielowiec, Jolanta, Huelsken, Joerg, Rosario, Marta, Birchmeier, Walter
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000540/
https://ncbi.nlm.nih.gov/pubmed/17881575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702555104
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