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FOXO and insulin signaling regulate sensitivity of the circadian clock to oxidative stress
Circadian rhythms can be regulated by many environmental and endogenous factors. We show here a sensitivity of circadian clock function to oxidative stress that is revealed in flies lacking the foxo gene product. When exposed to oxidative stress, wild-type flies showed attenuated clock gene cycling...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000406/ https://ncbi.nlm.nih.gov/pubmed/17895391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701599104 |
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