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Direct in vivo measurement of targeted binding in a human tumor xenograft

Binding is crucial to the function of most biologically active molecules, but difficult to quantify directly in living tissue. To this end, fluorescence recovery after photobleaching was used to detect the immobilization of fluorescently labeled ligand caused by binding to receptors in vivo. Measure...

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Detalhes bibliográficos
Main Authors: Berk, David A., Yuan, Fan, Leunig, Michael, Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19994/
https://ncbi.nlm.nih.gov/pubmed/9050856
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