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Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

The hyperpermeability of tumor vessels to macromolecules, compared with normal vessels, is presumably due to vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) released by neoplastic and/or host cells. In addition, VEGF/VPF is a potent angiogenic factor. Removal of this growt...

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Detalhes bibliográficos
Main Authors: Yuan, Fan, Chen, Yi, Dellian, Marc, Safabakhsh, Nina, Ferrara, Napoleone, Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26210/
https://ncbi.nlm.nih.gov/pubmed/8962129
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