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Insights into the influence of nucleotides on actin family proteins from seven new structures of Arp2/3 complex
ATP is required for nucleation of actin filament branches by Arp2/3 complex, but the influence of ATP binding and hydrolysis are poorly understood. We determined crystal structures of bovine Arp2/3 complex cocrystalized with various bound adenine nucleotides and cations. Nucleotide binding favors cl...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1997283/ https://ncbi.nlm.nih.gov/pubmed/17499050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.04.017 |
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