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Insights into the influence of nucleotides on actin family proteins from seven new structures of Arp2/3 complex

ATP is required for nucleation of actin filament branches by Arp2/3 complex, but the influence of ATP binding and hydrolysis are poorly understood. We determined crystal structures of bovine Arp2/3 complex cocrystalized with various bound adenine nucleotides and cations. Nucleotide binding favors cl...

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Bibliografske podrobnosti
Main Authors: Nolen, Brad J., Pollard, Thomas D.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1997283/
https://ncbi.nlm.nih.gov/pubmed/17499050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.04.017
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