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Na(+) Channel Mutation That Causes Both Brugada and Long-QT Syndrome Phenotypes: A Simulation Study of Mechanism

BACKGROUND: Complex physiological interactions determine the functional consequences of gene abnormalities and make mechanistic interpretation of phenotypes extremely difficult. A recent example is a single mutation in the C terminus of the cardiac Na(+) channel, 1795insD. The mutation causes two di...

詳細記述

保存先:
書誌詳細
主要な著者: Clancy, Colleen E., Rudy, Yoram
フォーマット: Artigo
言語:Inglês
出版事項: 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1997279/
https://ncbi.nlm.nih.gov/pubmed/11889015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/hc1002.105183
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