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Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation
The function of the 12 positive charges in the 53-residue III/IV interdomain linker of the cardiac Na(+) channel is unclear. We have identified a four-generation family, including 17 gene carriers with long QT syndrome, Brugada syndrome, and conduction system disease with deletion of lysine 1500 (ΔK...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150793/ https://ncbi.nlm.nih.gov/pubmed/12393856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15570 |
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