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Ataxin-1 Fusion Partners Alter PolyQ Lethality and Aggregation

Intranuclear inclusion bodies (IBs) are the histopathologic markers of multiple protein folding diseases. IB formation has been extensively studied using fluorescent fusion products of pathogenic polyglutamine (polyQ) expressing proteins. These studies have been informative in determining the cellul...

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Détails bibliographiques
Auteurs principaux: Rich, Tina, Varadaraj, Archana
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995763/
https://ncbi.nlm.nih.gov/pubmed/17925862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001014
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