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Review: mTOR at the crossroads of T cell proliferation and tolerance
Several events control the activation, proliferation, and the continued Ag responsiveness of naïve and memory T lymphocytes. Here we review the individual contributions of TCR, CD28, and IL-2-driven signaling to T cell proliferation and anergy avoidance. The role of mTOR as a rheostat capable of int...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995654/ https://ncbi.nlm.nih.gov/pubmed/17383196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2007.02.008 |
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