Autoinhibitory control of the Ca(V)1.2 channel by its proteolytically processed distal C-terminal domain

Voltage-gated Ca(2+) channels of the Ca(V)1 family initiate excitation–contraction coupling in cardiac, smooth, and skeletal muscle and are primary targets for regulation by the sympathetic nervous system in the ‘fight-or-flight’ response. In the heart, activation of β-adrenergic receptors greatly i...

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Bibliographic Details
Main Authors: Hulme, Joanne T, Yarov-Yarovoy, Vladimir, Lin, Teddy W-C, Scheuer, Todd, Catterall, William A
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2006
Subjects:
Molecular and Genomic
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995633/
https://ncbi.nlm.nih.gov/pubmed/16809371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.111799
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