Sites of proteolytic processing and noncovalent association of the distal C-terminal domain of Ca(V)1.1 channels in skeletal muscle

In skeletal muscle cells, voltage-dependent potentiation of Ca(2+) channel activity requires phosphorylation by cAMP-dependent protein kinase (PKA) anchored via an A-kinase anchoring protein (AKAP15), and the most rapid sites of phosphorylation are located in the C-terminal domain. Surprisingly, the...

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Detalhes bibliográficos
Main Authors: Hulme, Joanne T., Konoki, Keiichi, Lin, Teddy W.-C., Gritsenko, Marina A., Camp, David G., Bigelow, Diana J., Catterall, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC555994/
https://ncbi.nlm.nih.gov/pubmed/15793008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409885102
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