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Preferential block of inactivation-deficient Na(+) currents by capsaicin reveals a non-TRPV1 receptor within the Na(+) channel

Capsaicin elicits burning pain via the activation of the vanilloid receptor (TRPV1). Intriguingly, several reports showed that capsaicin also inhibits Na(+) currents but the mechanisms remain unclear. To explore this non-TRPV1 action we applied capsaicin to HEK293 cells stably expressing inactivatio...

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Библиографические подробности
Главные авторы: Wang, Sho-Ya, Mitchell, Jane, Wang, Ging Kuo
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995448/
https://ncbi.nlm.nih.gov/pubmed/16962240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2006.08.002
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