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The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion

The circumsporozoite protein (CSP) is the major surface protein of Plasmodium sporozoites, the infective stage of malaria. Although CSP has been extensively studied as a malaria vaccine candidate, little is known about its structure. Here, we show that CSP is proteolytically cleaved by a papain fami...

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Detalhes bibliográficos
Main Authors: Coppi, Alida, Pinzon-Ortiz, Consuelo, Hutter, Christina, Sinnis, Photini
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995445/
https://ncbi.nlm.nih.gov/pubmed/15630135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040989
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