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The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion

The circumsporozoite protein (CSP) is the major surface protein of Plasmodium sporozoites, the infective stage of malaria. Although CSP has been extensively studied as a malaria vaccine candidate, little is known about its structure. Here, we show that CSP is proteolytically cleaved by a papain fami...

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Bibliografiske detaljer
Main Authors: Coppi, Alida, Pinzon-Ortiz, Consuelo, Hutter, Christina, Sinnis, Photini
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995445/
https://ncbi.nlm.nih.gov/pubmed/15630135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040989
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