Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies

Studies in animals and human volunteers demonstrate that antibodies against the repeat-region of the Plasmodium circumsporozoite protein (CSP) abrogate sporozoite infection. However, the realization that the N- and C- terminal regions flanking the repeats play essential roles in parasite infectivity...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Espinosa, Diego A., Gutierrez, Gabriel M., Rojas-López, Maricarmen, Noe, Amy R., Shi, Lirong, Tse, Sze-Wah, Sinnis, Photini, Zavala, Fidel
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559189/
https://ncbi.nlm.nih.gov/pubmed/25762791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv154
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