Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo

Malaria-protective CD8+ T cells specific for the circumsporozoite (CS) protein are primed by dendritic cells (DCs) after sporozoite injection by infected mosquitoes. The primed cells then eliminate parasite liver stages after recognizing the CS epitopes presented by hepatocytes. To define the in viv...

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Bibliographische Detailangaben
Hauptverfasser: Cockburn, Ian A., Tse, Sze-Wah, Radtke, Andrea J., Srinivasan, Prakash, Chen, Yun-Chi, Sinnis, Photini, Zavala, Fidel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060173/
https://ncbi.nlm.nih.gov/pubmed/21445239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001318
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