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The Binding of the Circumsporozoite Protein to Cell Surface Heparan Sulfate Proteoglycans Is Required for Plasmodium Sporozoite Attachment to Target Cells

The major surface protein of malaria sporozoites, the circumsporozoite protein, binds to heparan sulfate proteoglycans on the surface of hepatocytes. It has been proposed that this binding event is responsible for the rapid and specific localization of sporozoites to the liver after their injection...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Pinzon-Ortiz, Consuelo, Friedman, Jennifer, Esko, Jeffrey, Sinnis, Photini
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2001
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941197/
https://ncbi.nlm.nih.gov/pubmed/11352923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M104038200
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