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Feeding Cultured Taxus Cells with Early Precursors Reveals Bifurcations in the Taxoid Biosynthetic Pathway

Feeding studies with Taxus suspension cells employing labeled 5α-hydroxytaxadiene and 5α,10β-dihydroxytaxadiene, and the corresponding 5α-acetate esters, demonstrated that acetylation at C5 of the monool precursor promotes the formation of 14β-hydroxy taxoids, such as taxuyunnanine C, at the expense...

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Detalhes bibliográficos
Main Authors: Ketchum, Raymond E.B., Horiguchi, Tohru, Qiu, Deyou, Williams, Robert M., Croteau, Rodney B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995239/
https://ncbi.nlm.nih.gov/pubmed/17157336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phytochem.2006.10.019
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