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CD4 and MHC-I Downregulation are Conserved in Primary HIV-1 Nef Alleles from Brain and Lymphoid Tissues, but Pak2 Activation is Highly Variable
HIV-1 compartmentalization in the CNS has been demonstrated for gag, pol, and env, genes. However, little is known about tissue compartmentalization of nef genes and their functional characteristics in brain. We have cloned 97 nef genes and characterized 10 Nef proteins from autopsy brain and lympho...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995023/ https://ncbi.nlm.nih.gov/pubmed/16979207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.07.053 |
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