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Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data

BACKGROUND: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental technologies, gene expression microarrays and Chromatin Immuno-Precipitation on Chip (ChIP-chip), are capable of producin...

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Détails bibliographiques
Auteurs principaux: Liu, Xiangdong, Jessen, Walter J, Sivaganesan, Siva, Aronow, Bruce J, Medvedovic, Mario
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994961/
https://ncbi.nlm.nih.gov/pubmed/17683565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-283
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