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The small GTP-binding protein Cdc42 is required for nerve growth factor withdrawal-induced neuronal death

An increase in the level of the c-Jun transcription factor and of its phosphorylation has previously been shown to be essential for nerve growth factor (NGF) withdrawal-induced apoptosis of rat sympathetic neurons (SCG). The Rho-like GTPases Cdc42 and Rac1 are involved in the regulation of a number...

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Detalles Bibliográficos
Main Authors: Bazenet, Chantal E., Mota, Mónica A., Rubin, Lee L.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC19949/
https://ncbi.nlm.nih.gov/pubmed/9520479
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