Characterisation of 11β-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat

Glucocorticoids (GCs) have a profound effect on adipose biology increasing tissue mass causing central obesity. The pre-receptor regulation of GCs by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) that activates cortisol from cortisone has been postulated as a fundamental mechanism underlying th...

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Bibliographic Details
Main Authors: Bujalska, Iwona J, Durrani, Omar M, Abbott, Joseph, Onyimba, Claire U, Khosla, Pamela, Moosavi, Areeb H, Reuser, Tristan T Q, Stewart, Paul M, Tomlinson, Jeremy W, Walker, Elizabeth A, Rauz, Saaeha
Format: Artigo
Language:Inglês
Published: Society for Endocrinology 2007
Subjects:
Regular Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994563/
https://ncbi.nlm.nih.gov/pubmed/17283228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-06-0042
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