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The antimalarial drugs quinine, chloroquine and mefloquine are antagonists at 5-HT(3) receptors
BACKGROUND AND PURPOSE: The antimalarial compounds quinine, chloroquine and mefloquine affect the electrophysiological properties of Cys-loop receptors and have structural similarities to 5-HT(3) receptor antagonists. They may therefore act at 5-HT(3) receptors. EXPERIMENTAL APPROACH: The effects of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1994240/ https://ncbi.nlm.nih.gov/pubmed/17502851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707238 |
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