Učitavanje...
Two Cys residues essential for von Willebrand factor multimer assembly in the Golgi
Von Willebrand factor (VWF) dimerizes through C-terminal CK domains, and VWF dimers assemble into multimers in the Golgi by forming intersubunit disulfide bonds between D3 domains. This unusual oxidoreductase reaction requires the VWF propeptide (domains D1D2), which acts as an endogenous pH-depende...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1994133/ https://ncbi.nlm.nih.gov/pubmed/17895385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705175104 |
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