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Crystal structure of a Kir3.1-prokaryotic Kir channel chimera

The Kir3.1 K(+) channel participates in heart rate control and neuronal excitability through G-protein and lipid signaling pathways. Expression in Escherichia coli has been achieved by replacing three fourths of the transmembrane pore with the pore of a prokaryotic Kir channel, leaving the cytoplasm...

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Detalhes bibliográficos
Main Authors: Nishida, Motohiko, Cadene, Martine, Chait, Brian T, MacKinnon, Roderick
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994128/
https://ncbi.nlm.nih.gov/pubmed/17703190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601828
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