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Essential role for TAX1BP1 in the termination of TNF-α-, IL-1- and LPS-mediated NF-κB and JNK signaling

The NF-κB transcription factor is normally transiently activated by proinflammatory cytokines and bacterial lipopolysaccharide (LPS); however, persistent NF-κB activation is commonly observed in inflammatory disease and malignancy. The ubiquitin editing enzyme A20 serves an essential role in the ter...

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Bibliografiske detaljer
Main Authors: Shembade, Noula, Harhaj, Nicole S, Liebl, Daniel J, Harhaj, Edward W
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994124/
https://ncbi.nlm.nih.gov/pubmed/17703191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601823
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