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An automated one-step one-pot [(18)F]FCWAY Synthesis: development and minimization of chemical impurities

[(18)F]FCWAY (N-{2-[4-(2-methoxyphenyl)piperazino]}-N-(2-pyridinyl)trans-4-fluorocyclohexanecarboxamide) has been prepared routinely as a serotonin 5-HT(1A) receptor ligand for clinical human studies. We have developed an automated one-step radiosynthesis using a modified Nuclear Interface C-11 Meth...

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Autors principals: Vuong, Bik-Kee, Kiesewetter, Dale O., Lang, Lixin, Ma, Ying, Eckelman, William C., Channing, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994052/
https://ncbi.nlm.nih.gov/pubmed/17499733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2007.03.001
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