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Automated Synthesis of (18)F Analogue of Paclitaxel (PAC): [(18)F]Paclitaxel (FPAC)

A positron-emitting paclitaxel (PAC) derivative could allow in-vivo measurement of multidrug resistance in tumors and, therefore, predict a potential chemotherapeutic benefit to patients. [(18)F]Paclitaxel was produced using a 2-reaction vessel automated synthesizer followed by HPLC purification. Op...

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Detalhes bibliográficos
Main Authors: Kalen, Joseph D., Hirsch, Jerry I., Kurdziel, Karen A., Eckelman, William C., Kiesewetter, Dale O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904428/
https://ncbi.nlm.nih.gov/pubmed/17161952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2006.10.015
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