Osteopontin Regulates Ubiquitin-Dependent Degradation of Stat1 in Murine Mammary Epithelial Tumor Cells

BACKGROUND: Osteopontin (OPN) is a secreted glycoprotein that mediates cell-matrix interactions and cellular signaling by binding with integrin (primarily α(v)β(3)) and CD44 receptors. OPN regulates cell adhesion, chemotaxis, macrophage-directed IL-10 suppression, stress-dependent angiogenesis, apop...

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Autores principales: Gao, Chengjiang, Mi, Zhiyong, Guo, Hongtao, Kuo, Paul C
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2007
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Brief Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993854/
https://ncbi.nlm.nih.gov/pubmed/17898865
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