Cyclooxygenase-2 Gene Disruption Promotes Proliferation of Murine Calvarial Osteoblasts In Vitro

Cyclooxygenase-2 (COX-2) is highly expressed in osteoblasts, and COX-2 produced prostaglandins (PGs) can increase osteoblastic differentiation in vitro. The goal of this study was to examine effects of COX-2 expression on calvarial osteoblastic proliferation and apoptosis. Primary osteoblasts (POBs)...

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Main Authors: Xu, Zheng, Choudhary, Shilpa, Okada, Yosuke, Voznesensky, Olga, Alander, Cynthia, Raisz, Lawrence, Pilbeam, Carol
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993538/
https://ncbi.nlm.nih.gov/pubmed/17467356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2007.03.009
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