Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells

Cystic fibrosis (CF) is a lethal inherited disease that results from abnormal chloride conduction in epithelial tissues. ClC-2 chloride channels are expressed in epithelia affected by CF and may provide a key “alternative” target for pharmacotherapy of this disease. To explore this possibility, the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Schwiebert, Erik M., Cid-Soto, Luis P., Stafford, Diane, Carter, Mark, Blaisdell, Carol J., Zeitlin, Pamela L., Guggino, William B., Cutting, Garry R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520461/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3879
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