Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells

Cystic fibrosis (CF) is a lethal inherited disease that results from abnormal chloride conduction in epithelial tissues. ClC-2 chloride channels are expressed in epithelia affected by CF and may provide a key “alternative” target for pharmacotherapy of this disease. To explore this possibility, the...

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Main Authors: Schwiebert, Erik M., Cid-Soto, Luis P., Stafford, Diane, Carter, Mark, Blaisdell, Carol J., Zeitlin, Pamela L., Guggino, William B., Cutting, Garry R.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19931/
https://ncbi.nlm.nih.gov/pubmed/9520461
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