Interferon α and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS

HIV type 1 (HIV-1) not only directly kills infected CD4(+) T cells but also induces immunosuppression of uninfected T cells. Two immunosuppressive proteins, interferon α (IFNα) and extracellular Tat, mediate this process because specific antibodies against these proteins prevent generation of suppre...

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Hlavní autoři: Zagury, Daniel, Lachgar, Abderrahim, Chams, Vida, Fall, Lat S., Bernard, Jacky, Zagury, Jean-François, Bizzini, Bernard, Gringeri, Alessandro, Santagostino, Elena, Rappaport, Jay, Feldman, Michael, Burny, Arsène, Gallo, Robert C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1998
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC19926/
https://ncbi.nlm.nih.gov/pubmed/9520456
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