Interferon α and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS

HIV type 1 (HIV-1) not only directly kills infected CD4(+) T cells but also induces immunosuppression of uninfected T cells. Two immunosuppressive proteins, interferon α (IFNα) and extracellular Tat, mediate this process because specific antibodies against these proteins prevent generation of suppre...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Zagury, Daniel, Lachgar, Abderrahim, Chams, Vida, Fall, Lat S., Bernard, Jacky, Zagury, Jean-François, Bizzini, Bernard, Gringeri, Alessandro, Santagostino, Elena, Rappaport, Jay, Feldman, Michael, Burny, Arsène, Gallo, Robert C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3851
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