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A Novel Method for KIR-ligand Typing by Pyrosequencing to Predict NK Cell Alloreactivity

Studies have shown that KIR-ligand mismatching to predict NK cell alloreactivity may result in less relapse and better survival in patients with AML. KIR-ligands are distinguished by single nucleotide polymorphisms (SNPs) from HLA-B and HLA-C sequences. We hypothesized that pyrosequencing to determi...

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Detalhes bibliográficos
Main Authors: Yun, Gong, Tolar, Jakub, Yerich, Anton K., Marsh, Steven G.E., Robinson, James, Noreen, Harriet, Blazar, Bruce R., Miller, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991282/
https://ncbi.nlm.nih.gov/pubmed/17446137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2007.01.011
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