Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity

We examined the clinical impact of killer-immunoglobulin receptor-ligand (KIR-L) mismatch in 257 recipients of single (n = 91) or double (n = 166) unit umbilical cord blood (UCB) grafts after myeloablative (n = 155) or reduced intensity (n = 102) conditioning regimens. Analyses of double unit grafts...

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Autori principali: Brunstein, Claudio G., Wagner, John E., Weisdorf, Daniel J., Cooley, Sarah, Noreen, Harriet, Barker, Juliet N., DeFor, Todd, Verneris, Michael R., Blazar, Bruce R., Miller, Jeffrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
Soggetti:
Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689057/
https://ncbi.nlm.nih.gov/pubmed/19329778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-197467
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