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Flexibility of Ras Lipid Modifications Studied by (2)H Solid-State NMR and Molecular Dynamics Simulations
Human posttranslationally modified N-ras oncogenes are known to be implicated in numerous human cancers. Here, we applied a combination of experimental and computational techniques to determine structural and dynamical details of the lipid chain modifications of an N-ras heptapeptide in 1,2-dimyrist...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1989704/ https://ncbi.nlm.nih.gov/pubmed/17557790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.104562 |
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